HitPredict

Interactor 1: ENT3 (P47160)
Epsin-3
Gene: ENT3

Interactor 2: VTI1 (Q04338)
t-SNARE VTI1 (Qb-SNARE VTI1) (VPS10-interacting protein 1) (Vesicle transport v-SNARE protein VTI1)
Gene: VTI1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.915

Property	Details
Experiments	21746902, 18033301, 14630930, 20658963
Identification Methods	isothermal titration calorimetry, pull down, two hybrid, x-ray crystallography, molecular sieving
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	ENTH~V-SNARE
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0006895 - Golgi to endosome transport GO:0006897 - endocytosis
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 408 Sc			1 217
+	At
		1147103 EPN2_ARATH (7-394): 2.44e-85: 279: 21.41		VTI12_ARATH (1-216): 5.94e-58: 184: 28.38
+	Hs
		1057127 EPN4_HUMAN (10-401): 1.12e-100: 313: 25.74		VTI1B_HUMAN (2-216): 4.2e-42: 144: 22.42
+	At
		1257776 EPN1_ARATH (9-401): 1.1e-78: 254: 23.41		VTI11_ARATH (1-216): 1.81e-56: 180: 29.86