Interactor 1: AKT1 (P47196)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: HS90A (P82995)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86)
Gene: Hsp90aa1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19356729
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP90~Pkinase
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 10 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 480
Rn

1 733
+ Mm
+ Hs
+ Mm
+ Bt
+ Hs
+ Hs
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+ Hs
+ Hs
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+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024