HitPredict

Interactor 1: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Interactor 2: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.866

Property	Details
Experiments	28894007, 33961781, 26824392
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 123 Hs			1 200
+	Hs
		812751 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20
+	Hs
		812735 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32
+	Hs
		812737 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB1A_HUMAN (1-200): 4.66e-87: 256: 50.24
+	Mm
		918998 MSS4_MOUSE (1-123): 1.15e-71: 211: 93.50		RAB1A_MOUSE (1-200): 4.66e-87: 256: 50.24
+	Hs
		812757 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB1B_HUMAN (3-200): 5.28e-86: 253: 50.50
+	Hs
		812732 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB13_HUMAN (4-174): 1.52e-83: 247: 69.59
+	Dm
		185729 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O18338_DROME (4-174): 9.35e-93: 271: 78.36
+	Dm
		185502 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O18332_DROME (1-200): 1.55e-86: 255: 52.68
+	Dm
		183445 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O15971_DROME (1-200): 1.23e-83: 247: 77.83