HitPredict

Interactor 1: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Interactor 2: RAB1A (P62820)
Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein)
Gene: RAB1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	12788069, 32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 123 Hs			1 205
+	Mm
		918998 MSS4_MOUSE (1-123): 1.15e-71: 211: 93.50		RAB1A_MOUSE (1-205): 4.45e-92: 269: 100.00
+	Hs
		812751 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		812757 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		812735 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Dm
		185502 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O18332_DROME (1-205): 5.89e-86: 254: 82.93
+	Dm
		185729 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O18338_DROME (4-175): 8.24e-74: 223: 60.47