HitPredict

Interactor 1: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Interactor 2: RAB8B (Q92930)
Ras-related protein Rab-8B
Gene: RAB8B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 123 Hs			1 207
+	Hs
		812736 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB10_HUMAN (1-197): 7.97e-95: 276: 70.20
+	Hs
		812737 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB1A_HUMAN (1-204): 9.22e-93: 271: 52.94
+	Mm
		918998 MSS4_MOUSE (1-123): 1.15e-71: 211: 93.50		RAB1A_MOUSE (1-204): 9.22e-93: 271: 52.94
+	Hs
		812757 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB1B_HUMAN (1-204): 3.94e-92: 269: 51.96
+	Hs
		812735 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB8A_HUMAN (1-207): 2.52e-91: 267: 82.61
+	Hs
		812732 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB13_HUMAN (1-206): 1.1e-88: 260: 64.08
+	Dm
		183445 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O15971_DROME (3-181): 4.71e-90: 264: 74.30
+	Dm
		185729 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O18338_DROME (1-207): 1.01e-89: 263: 78.74
+	Dm
		185502 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O18332_DROME (1-204): 4.01e-88: 259: 53.37