HitPredict

Interactor 1: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Interactor 2: RAB1B (Q9H0U4)
Ras-related protein Rab-1B (EC 3.6.5.2)
Gene: RAB1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.931

Property	Details
Experiments	28514442, 32296183, 33961781, 35271311, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 123 Hs			1 201
+	Hs
		812751 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB8B_HUMAN (1-200): 7.92e-92: 268: 52.45
+	Hs
		812737 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB1A_HUMAN (1-201): 5.62e-91: 266: 92.57
+	Mm
		918998 MSS4_MOUSE (1-123): 1.15e-71: 211: 93.50		RAB1A_MOUSE (1-201): 5.62e-91: 266: 92.57
+	Hs
		812732 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB13_HUMAN (1-200): 4.82e-82: 243: 51.50
+	Hs
		812735 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB8A_HUMAN (1-199): 1.31e-81: 243: 52.50
+	Dm
		185502 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O18332_DROME (2-201): 1.08e-85: 253: 83.58
+	Dm
		185729 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O18338_DROME (1-172): 2.31e-73: 222: 59.88
+	Dm
		183445 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O15971_DROME (5-201): 9.77e-73: 220: 54.04