HitPredict

Interactor 1: RP3A (P47708)
Rabphilin-3A (Exophilin-1)
Gene: Rph3a

Interactor 2: RB27B (Q99P58)
Ras-related protein Rab-27B (EC 3.6.5.2)
Gene: Rab27b

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12578829
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0006887 - exocytosis GO:0030141 - secretory granule GO:0030672 - synaptic vesicle membrane GO:0043197 - dendritic spine
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 681 Mm			1 218
+	Mm
		812772 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB3A_MOUSE (2-218): 6.28e-91: 267: 38.71
+	Mm
		812771 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB3C_MOUSE (2-218): 1.33e-89: 264: 39.45
+	Rn
		812780 RP3A_RAT (1-681): 0: 638: 97.52		RAB3A_RAT (2-218): 6.28e-91: 267: 38.71
+	Mm
		722679 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB3D_MOUSE (2-218): 7.35e-85: 252: 41.48
+	Mm
		812770 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB8A_MOUSE (2-217): 4.03e-79: 237: 38.43
+	Mm
		812778 RP3A_MOUSE (1-681): 0: 651: 100.00		RB27A_MOUSE (1-218): 2.01e-77: 233: 71.49
+	Hs
		591501 RP3A_HUMAN (1-681): 0: 601: 85.71		RAB3A_HUMAN (2-218): 1.31e-90: 267: 38.71
+	Hs
		119877 RP3A_HUMAN (1-681): 0: 601: 85.71		RB27B_HUMAN (1-218): 6.6e-86: 255: 94.50
+	Hs
		845961 RP3A_HUMAN (1-681): 0: 601: 85.71		RB27A_HUMAN (1-218): 9.36e-80: 239: 70.14
+	Hs
		1273014 RP3A_HUMAN (1-681): 0: 601: 85.71		RAB8B_HUMAN (2-217): 1.63e-79: 238: 37.50
+	Hs
		894828 RP3A_HUMAN (1-681): 0: 601: 85.71		RAB8A_HUMAN (2-216): 1.54e-79: 238: 38.61
+	Mm
		812777 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB3B_MOUSE (2-218): 7.3e-54: 173: 38.99
+	Hs
		591719 RP3A_HUMAN (1-681): 0: 601: 85.71		RAB3B_HUMAN (2-218): 1.28e-52: 170: 38.53
+	Dm
		284260 Q9W2R9_DROME (3-677): 2.81e-143: 434: 29.42		O76901_DROME (11-186): 1.7e-73: 224: 58.52
+	Hs
		591484 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RAB3A_HUMAN (2-218): 1.31e-90: 267: 38.71
+	Hs
		320135 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RAB3D_HUMAN (2-218): 2.11e-90: 266: 41.01
+	Hs
		119867 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RB27B_HUMAN (1-218): 6.6e-86: 255: 94.50
+	Hs
		845942 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RB27A_HUMAN (1-218): 9.36e-80: 239: 70.14
+	Hs
		894790 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RAB8A_HUMAN (2-216): 1.54e-79: 238: 38.61
+	Hs
		591654 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RAB3B_HUMAN (2-218): 1.28e-52: 170: 38.53