HitPredict

Interactor 1: RP3A (P47708)
Rabphilin-3A (Exophilin-1)
Gene: Rph3a

Interactor 2: RB27A (Q9ERI2)
Ras-related protein Rab-27A (EC 3.6.5.2)
Gene: Rab27a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	12578829, 11773082, 14722103
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0006887 - exocytosis GO:0030141 - secretory granule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 681 Mm			1 221
+	Mm
		722679 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB3D_MOUSE (2-221): 1.04e-85: 254: 40.46
+	Mm
		812776 RP3A_MOUSE (1-681): 0: 651: 100.00		RB27B_MOUSE (1-221): 4.19e-77: 232: 71.49
+	Hs
		845961 RP3A_HUMAN (1-681): 0: 601: 85.71		RB27A_HUMAN (1-221): 3.76e-82: 245: 95.93
+	Hs
		119877 RP3A_HUMAN (1-681): 0: 601: 85.71		RB27B_HUMAN (1-221): 6e-78: 234: 71.95
+	Mm
		812772 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB3A_MOUSE (2-192): 9.5e-57: 181: 43.98
+	Mm
		812771 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB3C_MOUSE (2-190): 2.83e-56: 180: 43.92
+	Mm
		812777 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB3B_MOUSE (2-190): 3.02e-55: 177: 44.44
+	Mm
		812770 RP3A_MOUSE (1-681): 0: 651: 100.00		RAB8A_MOUSE (6-187): 1.15e-53: 172: 46.70
+	Rn
		812780 RP3A_RAT (1-681): 0: 638: 97.52		RAB3A_RAT (2-192): 9.5e-57: 181: 43.98
+	Hs
		591501 RP3A_HUMAN (1-681): 0: 601: 85.71		RAB3A_HUMAN (2-192): 8.9e-57: 181: 43.98
+	Hs
		591719 RP3A_HUMAN (1-681): 0: 601: 85.71		RAB3B_HUMAN (2-190): 1.87e-54: 175: 43.92
+	Hs
		894828 RP3A_HUMAN (1-681): 0: 601: 85.71		RAB8A_HUMAN (6-187): 9.19e-54: 172: 46.70
+	Hs
		1273014 RP3A_HUMAN (1-681): 0: 601: 85.71		RAB8B_HUMAN (6-192): 3.9e-53: 171: 44.39
+	Dm
		284260 Q9W2R9_DROME (3-677): 2.81e-143: 434: 29.42		O76901_DROME (11-186): 5.19e-79: 238: 61.36
+	Hs
		845942 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RB27A_HUMAN (1-221): 3.76e-82: 245: 95.93
+	Hs
		119867 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RB27B_HUMAN (1-221): 6e-78: 234: 71.95
+	Hs
		591484 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RAB3A_HUMAN (2-192): 8.9e-57: 181: 43.98
+	Hs
		320135 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RAB3D_HUMAN (2-190): 1.75e-56: 180: 43.92
+	Hs
		591654 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RAB3B_HUMAN (2-190): 1.87e-54: 175: 43.92
+	Hs
		894790 SYTL4_HUMAN (46-673): 3.64e-124: 385: 22.07		RAB8A_HUMAN (6-187): 9.19e-54: 172: 46.70