HitPredict

Interactor 1: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Interactor 2: DAPK1 (P53355)
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene: DAPK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	25852190, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~F-actin_cap_A
Common GO terms	GO:0015629 - actin cytoskeleton
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 1430
+	Hs
		857088 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		DAPK1_HUMAN (1-1430): 0: 1999: 100.00
+	Hs
		200095 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		DAPK3_HUMAN (1-376): 1.82e-120: 385: 60.00
+	Rn
		506728 CAZA2_RAT (1-286): 4.17e-159: 445: 98.25		KCC2A_RAT (1-383): 5.07e-120: 385: 29.17
+	Rn
		70294 CAZA1_RAT (1-286): 1.44e-157: 441: 86.71		KCC2A_RAT (1-383): 5.07e-120: 385: 29.17
+	Hs
		857104 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		ANK2_HUMAN (248-797): 3.54e-109: 385: 19.42