HitPredict

Interactor 1: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0015629 - actin cytoskeleton
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 793
+	Hs
		857106 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		813116 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		725107 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63
+	Hs
		857183 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		813225 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29
+	Hs
		724703 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		724728 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		813037 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		148516 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		148566 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		813177 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		857226 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38