HitPredict

Interactor 1: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	26638075, 28514442, 26186194, 26496610, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 1278
+	Hs
		857124 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		725107 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13
+	Ss
		49076 CAZA1_PIG (1-286): 1.56e-155: 436: 87.06		MYH2_PIG (680-1266): 6.72e-25: 115: 9.90
+	Hs
		675134 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32
+	Hs
		724703 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		724728 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54