HitPredict

Interactor 1: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Interactor 2: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0030036 - actin cytoskeleton organization
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 1117
+	Hs
		813054 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		CYTSB_HUMAN (167-1117): 3.95e-60: 226: 38.76
+	Hs
		521495 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Hs
		211527 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		211540 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		813100 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MILK1_HUMAN (1011-1115): 2.96e-36: 150: 41.51
+	Hs
		724703 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		725107 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH10_HUMAN (213-1075): 1.21e-33: 143: 10.62
+	Hs
		724728 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Ss
		49076 CAZA1_PIG (1-286): 1.56e-155: 436: 87.06		MYH2_PIG (3-601): 1.14e-22: 107: 8.00