HitPredict

Interactor 1: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Interactor 2: CRACD (Q6ZU35)
Capping protein-inhibiting regulator of actin dynamics (Cancer-related regulator of actin dynamics)
Gene: CRACD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 26496610, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 1233
+	Hs
		857158 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		CRACD_HUMAN (1-1233): 0: 570: 100.00
+	Hs
		99713 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		F5H1N7_HUMAN (41-1233): 6.42e-173: 546: 100.00
+	Hs
		813024 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		DCTN1_HUMAN (83-539): 1.36e-36: 152: 19.62
+	Hs
		857124 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		DCTN1_HUMAN (83-539): 1.36e-36: 152: 19.62
+	Hs
		725107 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH10_HUMAN (149-782): 1.39e-23: 110: 9.39
+	Ss
		49076 CAZA1_PIG (1-286): 1.56e-155: 436: 87.06		MYH2_PIG (12-741): 1.75e-25: 117: 8.03
+	Hs
		724703 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		724728 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		813037 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		PLEC_HUMAN (69-693): 1.83e-11: 71.2: 10.88
+	Hs
		813177 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYO5C_HUMAN (265-545): 5.44e-10: 66.1: 14.39
+	Hs
		148516 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		857226 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		MYO5C_HUMAN (265-545): 5.44e-10: 66.1: 14.39
+	Hs
		148566 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27