HitPredict

Interactor 1: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding GO:0051016 - barbed-end actin filament capping
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 2365
+	Hs
		813077 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		724703 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		725107 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89
+	Hs
		724728 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		813037 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		857128 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		MDC1_HUMAN (88-903): 1.81e-15: 85.4: 14.49
+	Hs
		108760 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		H0Y2S9_HUMAN (1977-2364): 3.99e-11: 71.2: 17.72
+	Hs
		857104 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82