HitPredict

Interactor 1: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB

Interactor 2: DAPK1 (P53355)
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene: DAPK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	25852190, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~F_actin_cap_B
Common GO terms	GO:0014069 - postsynaptic density GO:0015629 - actin cytoskeleton
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 1430
+	Hs
		200096 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		DAPK3_HUMAN (1-376): 1.82e-120: 385: 60.00
+	Rn
		506737 CAPZB_RAT (1-272): 4.35e-177: 490: 100.00		KCC2A_RAT (1-383): 5.07e-120: 385: 29.17
+	Hs
		813834 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		ANR50_HUMAN (250-749): 3.44e-97: 345: 21.39
+	Hs
		813495 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		MYLK_HUMAN (1-319): 4.96e-76: 281: 44.06