HitPredict

Interactor 1: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 35271311, 35235311, 34349018, 30021884, 37071682
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~F_actin_cap_B
Common GO terms GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005903 - brush border
GO:0015629 - actin cytoskeleton
GO:0016020 - membrane
and 4 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 272
Hs

1 375
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024