HitPredict

Interactor 1: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	28514442, 27173435, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 1278
+	Hs
		725108 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13
+	Hs
		675135 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32
+	Hs
		724704 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		728455 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		MYH11_HUMAN (49-439): 7.24e-12: 72.5: 9.16