Interactor 1: MP2K4 (P47809)
Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1)
Gene: Map2k4

Interactor 2: MK10 (Q61831)
Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)
Gene: Mapk10

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 15218018
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0007254 - JNK cascade
GO:0043204 - perikaryon
GO:0106310 - protein serine kinase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 397
Mm

1 464
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Rn
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ At
+ Mm
+ Hs
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024