HitPredict

Interactor 1: MK14 (P47811)
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (CRK1) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha)
Gene: Mapk14

Interactor 2: MAPK2 (P49138)
MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1)
Gene: Mapkapk2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.800

The method score is based on:

Property Details
Experiments 15538386, 19369945
Identification Methods two hybrid, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 7 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 360
Mm

1 386
+ Hs
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+ At
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+ At
+ Dm
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+ At
+ At
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+ Hs
+ Mm
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+ Rn
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+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024