Interactor 1: FEN1 (P39748)
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1)
Gene: FEN1

Interactor 2: FEN1 (P39748)
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1)
Gene: FEN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains XPG_I~XPG_I, XPG_I~XPG_N, XPG_N~XPG_N
Common GO terms GO:0000287 - magnesium ion binding
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0003684 - damaged DNA binding
GO:0003677 - DNA binding
and 24 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 380
Hs

1 380
+ Ce
+ Dm
+ Bs

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Last updated: 11Aug2025