Interactor 1: SLN1 (P39928)
Osmosensing histidine protein kinase SLN1 (EC 2.7.13.3) (Osmolarity two-component system protein SLN1) (Tyrosine phosphatase-dependent protein 2)
Gene: SLN1
Interactor 2: YPD1 (Q07688)
Phosphorelay intermediate protein YPD1 (Histidine-containing phosphotransfer protein YPD1) (Tyrosine phosphatase-dependent protein 1)
Gene: YPD1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.976 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8808622, 14656441, 15628880, 9882653, 15769590, 28380353, 30665347, 18076904, 12455952, 17559414, 19618914 |
| Identification Methods | two hybrid, biochemical, x-ray crystallography, enzymatic study, pull down |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hpt~Response_reg |
| Common GO terms | GO:0000160 - phosphorelay signal transduction system GO:0007234 - osmosensory signaling via phosphorelay pathway GO:0009927 - histidine phosphotransfer kinase activity |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
