HitPredict

Interactor 1: CRKL (P47941)
Crk-like protein
Gene: CRKL

Interactor 2: CBLB (Q3TTA7)
E3 ubiquitin-protein ligase CBL-B (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene b) (RING-type E3 ubiquitin transferase CBL-B) (SH3-binding protein CBL-B) (Signal transduction protein CBL-B)
Gene: CBLB

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.588

The method score is based on:

Property Details
Experiments 12697763, 27474268
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001784 - phosphotyrosine residue binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0030971 - receptor tyrosine kinase binding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 303
Mm

1 982
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Last updated: 15 Jul 2024