HitPredict

Interactor 1: DPYL2 (P47942)
Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (Turned on after division 64 kDa protein) (TOAD-64)
Gene: Dpysl2

Interactor 2: NMDE2 (Q00960)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)
Gene: Grin2b

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17670980
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001975 - response to amphetamine GO:0005856 - cytoskeleton GO:0014049 - positive regulation of glutamate secretion GO:0016020 - membrane GO:0042220 - response to cocaine and 2 others more... GO:0043025 - neuronal cell body GO:0045202 - synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 572 Rn			1 1482
+	Hs
		1028141 DPYL2_HUMAN (1-572): 0: 780: 98.78		NMDE2_HUMAN (1-1482): 0: 1828: 98.38
+	Rn
		815105 DPYL2_RAT (1-572): 0: 779: 100.00		NMDE1_RAT (9-1482): 0: 1498: 52.31
+	Rn
		723622 DPYL2_RAT (1-572): 0: 779: 100.00		NMDZ1_RAT (14-940): 0: 676: 24.14
+	Hs
		1060489 DPYL5_HUMAN (13-567): 0: 662: 52.24		NMDE3_HUMAN (9-929): 0: 765: 53.95
+	Rn
		585203 DPYL2_RAT (1-572): 0: 779: 100.00		GRIA4_RAT (16-852): 0: 644: 20.89
+	Hs
		1048472 DPYS_HUMAN (16-530): 0: 648: 59.73		NMDE3_HUMAN (9-929): 0: 765: 53.95
+	Hs
		653193 PYR1_HUMAN (26-530): 3.24e-127: 413: 18.08		GRIA4_HUMAN (16-852): 0: 647: 20.89