HitPredict

Interactor 1: TISD (P47974)
mRNA decay activator protein ZFP36L2 (Butyrate response factor 2) (EGF-response factor 2) (ERF-2) (TPA-induced sequence 11d) (Zinc finger protein 36, C3H1 type-like 2) (ZFP36-like 2)
Gene: ZFP36L2

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	29449217, 33961781, 36931259, 17979178, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 246
+	Hs
		815212 TISD_HUMAN (1-494): 5.62e-105: 324: 100.00		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		815209 TISD_HUMAN (1-494): 5.62e-105: 324: 100.00		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		815222 TISD_HUMAN (1-494): 5.62e-105: 324: 100.00		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683197 TISD_HUMAN (1-494): 5.62e-105: 324: 100.00		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		646718 TISD_HUMAN (1-494): 5.62e-105: 324: 100.00		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		683898 TISD_HUMAN (1-494): 5.62e-105: 324: 100.00		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		644242 TTP_HUMAN (92-393): 3.77e-32: 127: 28.71		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		909474 TISB_HUMAN (414-494): 2.77e-10: 63.6: 57.32		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		904481 TISB_HUMAN (414-494): 2.77e-10: 63.6: 57.32		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		981948 TISB_HUMAN (414-494): 2.77e-10: 63.6: 57.32		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Mm
		612137 TTP_MOUSE (59-393): 1.35e-35: 136: 26.71		1433B_MOUSE (3-245): 9.94e-107: 310: 75.92
+	Hs
		644231 TTP_HUMAN (92-393): 3.77e-32: 127: 28.71		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		644227 TTP_HUMAN (92-393): 3.77e-32: 127: 28.71		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		926962 TISB_HUMAN (414-494): 2.77e-10: 63.6: 57.32		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683291 TISB_HUMAN (414-494): 2.77e-10: 63.6: 57.32		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		646828 TISB_HUMAN (414-494): 2.77e-10: 63.6: 57.32		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		683988 TISB_HUMAN (414-494): 2.77e-10: 63.6: 57.32		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20