HitPredict

Interactor 1: TNFL6 (P48023)
Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]
Gene: FASLG

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19807924
Identification Methods	unspecified method, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 281 Hs			1 347
+	Hs
		815719 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		PACN2_HUMAN (1-343): 3.2e-38: 143: 16.45
+	Hs
		815712 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		PACN1_HUMAN (6-342): 5.44e-34: 131: 14.90
+	Hs
		815701 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		SH3R2_HUMAN (266-340): 5.72e-15: 77.8: 36.15
+	Hs
		815671 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38