HitPredict

Interactor 1: TNFL6 (P48023)
Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]
Gene: FASLG

Interactor 2: BI2L1 (Q9UHR4)
BAR/IMD domain-containing adapter protein 2-like 1 (Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1) (BAI1-associated protein 2-like protein 1) (Insulin receptor tyrosine kinase substrate)
Gene: BAIAP2L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19807924
Identification Methods	unspecified method, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 281 Hs			1 511
+	Hs
		815719 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		815712 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		PACN1_HUMAN (7-400): 2.59e-83: 266: 13.10
+	Hs
		815718 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		PACN3_HUMAN (7-400): 5.44e-74: 242: 12.71
+	Hs
		207781 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		PPIP1_HUMAN (10-400): 3.63e-66: 221: 14.61
+	Hs
		207808 Q53ZZ1_HUMAN (1-281): 1.11e-121: 350: 100.00		PPIP1_HUMAN (10-400): 3.63e-66: 221: 14.61
+	Mm
		780475 TNFL6_MOUSE (1-281): 1.01e-121: 350: 75.09		PPIP1_MOUSE (10-400): 9.13e-65: 217: 13.82
+	Hs
		815714 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		ITSN2_HUMAN (225-399): 4.87e-10: 64.6: 14.29