HitPredict

Interactor 1: TNFL6 (P48023)
Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]
Gene: FASLG

Interactor 2: SNX9 (Q9Y5X1)
Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A)
Gene: SNX9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	26186194, 19807924, 24291222
Identification Methods	affinity chromatography technology, unspecified method, anti tag coimmunoprecipitation, phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 281 Hs			1 595
+	Hs
		815702 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73
+	Hs
		815707 TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00		SNX18_HUMAN (1-519): 3.5e-123: 379: 33.09