HitPredict

Interactor 1: KSYK (P48025)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase)
Gene: Syk

Interactor 2: Q5U3L0 (Q5U3L0)
SH3-domain binding protein 2 (Sh3bp2 protein)
Gene: Sh3bp2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	22153076
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, SH2~SH2
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 629 Mm			1 559
+	Hs
		796543 KSYK_HUMAN (2-629): 0: 594: 91.94		3BP2_HUMAN (1-559): 0: 886: 85.92
+	Hs
		796467 ZAP70_HUMAN (5-629): 0: 566: 52.88		3BP2_HUMAN (1-559): 0: 886: 85.92
+	Hs
		507946 FGFR1_HUMAN (186-629): 3.21e-118: 372: 26.33		3BP2_HUMAN (1-559): 0: 886: 85.92
+	Mm
		403436 SRC_MOUSE (1-130): 7.67e-37: 146: 26.81		Q5U3L0_MOUSE (1-559): 0: 1004: 100.00
+	Hs
		940669 ERBB4_HUMAN (371-613): 3.07e-56: 208: 43.50		3BP2_HUMAN (1-559): 0: 886: 85.92
+	Hs
		383735 ERBB2_HUMAN (371-613): 9.63e-52: 194: 42.28		3BP2_HUMAN (1-559): 0: 886: 85.92
+	Mm
		337628 ABL1_MOUSE (3-112): 4.65e-12: 71.5: 27.43		3BP2_MOUSE (1-559): 0: 1004: 99.64
+	Hs
		412125 FYN_HUMAN (1-130): 7.17e-43: 163: 23.91		3BP2_HUMAN (1-559): 0: 886: 85.92
+	Hs
		411669 LCK_HUMAN (1-114): 1.76e-40: 156: 29.51		3BP2_HUMAN (1-559): 0: 886: 85.92
+	Hs
		522898 SRC_HUMAN (1-130): 7.76e-37: 146: 26.81		3BP2_HUMAN (1-559): 0: 886: 85.92
+	Hs
		337423 ABL1_HUMAN (3-112): 4.58e-12: 71.5: 27.43		3BP2_HUMAN (1-559): 0: 886: 85.92