HitPredict

Interactor 1: KSYK (P48025)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase)
Gene: Syk

Interactor 2: TRAF3 (Q60803)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 23962979
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0019901 - protein kinase binding
GO:0031625 - ubiquitin protein ligase binding
GO:0032481 - positive regulation of type I interferon production
GO:0045087 - innate immune response
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 629
Mm

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024