HitPredict

Interactor 1: KSYK (P48025)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase)
Gene: Syk

Interactor 2: CLC7A (Q6QLQ4)
C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (CD antigen CD369)
Gene: Clec7a

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.702

The method score is based on:

Property Details
Experiments 34362877, 18200499, 15845454, 18408006, 22689578
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001775 - cell activation
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0002366 - leukocyte activation involved in immune response
GO:0032733 - positive regulation of interleukin-10 production
GO:0032755 - positive regulation of interleukin-6 production
and 6 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 629
Mm

1 244
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024