HitPredict

Interactor 1: KCNJ4 (P48050)
Inward rectifier potassium channel 4 (HIRK2) (HRK1) (Hippocampal inward rectifier) (HIR) (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)
Gene: KCNJ4

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	24550280, 30126976
Identification Methods	phage display, p8 filamentous phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 1630
+	Hs
		1049947 KCJ12_HUMAN (7-445): 0: 660: 63.86		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		929767 KCNJ2_HUMAN (7-445): 0: 641: 60.46		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		816146 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG4_HUMAN (812-1187): 3.22e-49: 190: 22.42
+	Mm
		852403 KCNJ4_MOUSE (1-445): 0: 691: 96.86		DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42
+	Hs
		942342 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG4_HUMAN (812-1187): 3.22e-49: 190: 22.42
+	Mm
		1143540 Q9QYK8_MOUSE (9-439): 0: 657: 97.45		DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42
+	Rn
		677769 KCJ12_RAT (7-445): 0: 648: 63.55		DLG4_RAT (812-1187): 3.08e-49: 190: 22.42
+	Hs
		929762 KCNJ2_HUMAN (7-445): 0: 641: 60.46		DLG4_HUMAN (812-1187): 3.22e-49: 190: 22.42
+	Hs
		816150 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG2_HUMAN (587-879): 1.21e-20: 101: 18.67
+	Hs
		816147 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		1054723 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG2_HUMAN (587-879): 1.21e-20: 101: 18.67
+	Hs
		1054724 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Rn
		852400 KCJ12_RAT (7-445): 0: 648: 63.55		DLG2_RAT (587-879): 2.66e-21: 103: 18.52
+	Rn
		852399 KCJ12_RAT (7-445): 0: 648: 63.55		DLG3_RAT (724-947): 3.57e-19: 96.3: 31.23
+	Hs
		1021490 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Rn
		1144360 KCNJ2_RAT (7-445): 0: 638: 61.36		DLG2_RAT (587-879): 2.66e-21: 103: 18.52
+	Hs
		80982 KCJ18_HUMAN (7-445): 0: 654: 63.41		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Rn
		852397 KCJ12_RAT (7-445): 0: 648: 63.55		DLG1_RAT (679-910): 1.87e-14: 80.9: 22.79
+	Hs
		929764 KCNJ2_HUMAN (7-445): 0: 641: 60.46		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Rn
		1144015 KCNJ2_RAT (7-445): 0: 638: 61.36		DLG1_RAT (679-910): 1.87e-14: 80.9: 22.79