HitPredict

Interactor 1: KCNJ4 (P48050)
Inward rectifier potassium channel 4 (HIRK2) (HRK1) (Hippocampal inward rectifier) (HIR) (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)
Gene: KCNJ4

Interactor 2: DLG2 (Q15700)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11997254
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 870
+	Hs
		1054723 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG2_HUMAN (1-870): 0: 755: 100.00
+	Rn
		852400 KCJ12_RAT (7-445): 0: 648: 63.55		DLG2_RAT (1-870): 0: 740: 94.94
+	Hs
		159173 KCNJ4_HUMAN (1-445): 0: 690: 100.00		CSKP_HUMAN (24-307): 6.74e-22: 104: 10.62
+	Hs
		816147 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Mm
		852403 KCNJ4_MOUSE (1-445): 0: 691: 96.86		DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93
+	Hs
		816146 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Hs
		159210 KCJ12_HUMAN (7-445): 0: 660: 63.86		CSKP_HUMAN (24-307): 6.74e-22: 104: 10.62
+	Rn
		852398 KCJ12_RAT (7-445): 0: 648: 63.55		CSKP_RAT (24-448): 2.31e-23: 108: 9.39
+	Hs
		1021490 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Hs
		1054729 KCJ12_HUMAN (7-445): 0: 660: 63.86		PALS2_HUMAN (8-234): 1.66e-17: 88.7: 17.46
+	Hs
		942342 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Hs
		80982 KCJ18_HUMAN (7-445): 0: 654: 63.41		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Mm
		1143540 Q9QYK8_MOUSE (9-439): 0: 657: 97.45		DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93
+	Rn
		852397 KCJ12_RAT (7-445): 0: 648: 63.55		DLG1_RAT (271-503): 5.38e-17: 87.9: 17.19
+	Rn
		677769 KCJ12_RAT (7-445): 0: 648: 63.55		DLG4_RAT (375-573): 1.69e-16: 86.4: 22.93
+	Hs
		1054724 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG3_HUMAN (317-573): 1.1e-12: 74.1: 19.40
+	Hs
		929764 KCNJ2_HUMAN (7-445): 0: 641: 60.46		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Rn
		852399 KCJ12_RAT (7-445): 0: 648: 63.55		DLG3_RAT (273-573): 1.44e-15: 83.3: 16.23
+	Hs
		929762 KCNJ2_HUMAN (7-445): 0: 641: 60.46		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Rn
		1144015 KCNJ2_RAT (7-445): 0: 638: 61.36		DLG1_RAT (271-503): 5.38e-17: 87.9: 17.19