HitPredict

Interactor 1: KCNJ4 (P48050)
Inward rectifier potassium channel 4 (HIRK2) (HRK1) (Hippocampal inward rectifier) (HIR) (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)
Gene: KCNJ4

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15024025, 14960569
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 197
+	Hs
		816152 KCNJ4_HUMAN (1-445): 0: 690: 100.00		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		158266 KCNJ4_HUMAN (1-445): 0: 690: 100.00		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		1054728 KCJ12_HUMAN (7-445): 0: 660: 63.86		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Hs
		1054726 KCJ12_HUMAN (7-445): 0: 660: 63.86		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		158284 KCJ12_HUMAN (7-445): 0: 660: 63.86		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		159173 KCNJ4_HUMAN (1-445): 0: 690: 100.00		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		816148 KCNJ4_HUMAN (1-445): 0: 690: 100.00		SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80
+	Hs
		816150 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG2_HUMAN (23-196): 1.68e-25: 104: 23.63
+	Mm
		852403 KCNJ4_MOUSE (1-445): 0: 691: 96.86		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		816146 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		816147 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		1033871 KCJ12_HUMAN (7-445): 0: 660: 63.86		SNTB2_HUMAN (61-179): 3e-32: 123: 35.25
+	Hs
		1033833 KCJ12_HUMAN (7-445): 0: 660: 63.86		SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80
+	Hs
		1046429 KCJ12_HUMAN (7-445): 0: 660: 63.86		SNTB1_HUMAN (65-179): 5.68e-31: 119: 35.90
+	Hs
		159210 KCJ12_HUMAN (7-445): 0: 660: 63.86		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		1054723 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG2_HUMAN (23-196): 1.68e-25: 104: 23.63
+	Hs
		942342 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		1021490 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Mm
		1143540 Q9QYK8_MOUSE (9-439): 0: 657: 97.45		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		1054724 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG3_HUMAN (74-164): 2.8e-20: 89.8: 35.42