Interactor 1: KCNJ6 (P48051)
G protein-activated inward rectifier potassium channel 2 (GIRK-2) (BIR1) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (Potassium channel, inwardly rectifying subfamily J member 6)
Gene: KCNJ6

Interactor 2: KCNJ9 (Q92806)
G protein-activated inward rectifier potassium channel 3 (GIRK-3) (Inward rectifier K(+) channel Kir3.3) (Potassium channel, inwardly rectifying subfamily J member 9)
Gene: KCNJ9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 10956667, 12297500
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRK~IRK, IRK~IRK_C, IRK_C~IRK_C
Common GO terms GO:0005242 - inward rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0015467 - G-protein activated inward rectifier potassium channel activity
GO:0034765 - regulation of monoatomic ion transmembrane transport
GO:1990573 - potassium ion import across plasma membrane
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 423
Hs

1 393
+ Mm
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+ Bt
+ Gg
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024