HitPredict

Interactor 1: GRIA4 (P48058)
Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4)
Gene: GRIA4

Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	11891216
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030666 - endocytic vesicle membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 902 Hs			1 415
+	Rn
		585217 GRIA4_RAT (1-902): 0: 916: 98.23		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		786710 GRIA1_HUMAN (4-901): 0: 861: 66.16		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		585195 GRIA3_RAT (2-862): 0: 840: 72.95		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		786764 GRIA3_HUMAN (2-862): 0: 843: 73.41		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		585182 GRIA2_RAT (1-849): 0: 824: 73.30		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		786746 GRIA2_HUMAN (1-849): 0: 825: 73.42		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		786686 GRIK2_RAT (2-901): 0: 812: 37.08		PICK1_RAT (1-415): 0: 597: 96.39
+	Mm
		620964 GRIA2_MOUSE (1-849): 0: 824: 73.30		PICK1_MOUSE (1-415): 0: 584: 94.47
+	Hs
		1022367 GRIK2_HUMAN (3-901): 0: 813: 37.01		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		611607 GRIK1_RAT (8-878): 0: 770: 36.77		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		761212 GRIK1_HUMAN (7-848): 0: 768: 37.41		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Hs
		1060472 NMDE3_HUMAN (11-889): 0: 598: 22.83		ICA1L_HUMAN (143-387): 1.08e-74: 242: 14.92