Interactor 1: LIMS1 (P48059)
LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) (Renal carcinoma antigen NY-REN-48)
Gene: LIMS1

Interactor 2: RSU1 (Q15404)
Ras suppressor protein 1 (RSP-1) (Rsu-1)
Gene: RSU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.954

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 25416956, 23414517, 29892012
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid fragment pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains LIM~LRR_8
Common GO terms GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0010811 - positive regulation of cell-substrate adhesion
GO:0043547 - positive regulation of GTPase activity
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 325
Hs

1 277
+ Hs
+ Ce
+ Dm
+ Dm
+ Dm
+ Hs

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Last updated: 15 Jul 2024