HitPredict

Interactor 1: SDF1 (P48061)
Stromal cell-derived factor 1 (SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF) [Cleaved into: SDF-1-beta(3-72); SDF-1-alpha(3-67)]
Gene: CXCL12

Interactor 2: CCR4 (P51679)
C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194)
Gene: CCR4

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.36 1.00 0.607

The method score is based on:

Property Details
Experiments 10556181, 11527993
Identification Methods experimental interaction detection
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~IL8
Common GO terms GO:0006935 - chemotaxis
GO:0006955 - immune response
GO:0009897 - external side of plasma membrane
GO:0060326 - cell chemotaxis
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 93
Hs

1 360
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024