HitPredict

Interactor 1: RHO1 (P48148)
Ras-like GTP-binding protein Rho1
Gene: RHO1

Interactor 2: M3KSL (Q95UN8)
Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase) (Protein slipper) (dMLK)
Gene: slpr

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20404112
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005938 - cell cortex GO:0007391 - dorsal closure
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 1161
+	Dm
		776899 RAC1_DROME (1-192): 3.06e-78: 233: 54.64		M3KSL_DROME (1-1161): 0: 1115: 100.00
+	Dm
		87957 RHO1_DROME (1-192): 2.16e-78: 233: 100.00		D3DMF6_DROME (125-944): 7.25e-148: 470: 21.15
+	Hs
		925309 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		M3K11_HUMAN (50-826): 3.16e-142: 452: 35.27
+	Hs
		951023 RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21		M3K11_HUMAN (50-826): 3.16e-142: 452: 35.27
+	Hs
		925212 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		M3K10_HUMAN (55-895): 1.6e-135: 437: 34.32
+	Hs
		433314 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		YES_HUMAN (1-414): 1.82e-127: 403: 25.93
+	Hs
		522888 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		SRC_HUMAN (1-414): 6.27e-127: 401: 25.46
+	Hs
		433307 RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53		YES_HUMAN (1-414): 1.82e-127: 403: 25.93
+	Hs
		433322 RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21		YES_HUMAN (1-414): 1.82e-127: 403: 25.93
+	Hs
		412123 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		FYN_HUMAN (1-414): 1.17e-124: 395: 24.37
+	Hs
		433239 RAC2_HUMAN (1-192): 3.29e-77: 230: 55.16		YES_HUMAN (1-414): 1.82e-127: 403: 25.93
+	Hs
		412115 RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53		FYN_HUMAN (1-414): 1.17e-124: 395: 24.37
+	Hs
		411980 RAC2_HUMAN (1-192): 3.29e-77: 230: 55.16		FYN_HUMAN (1-414): 1.17e-124: 395: 24.37
+	Hs
		433685 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		LYN_HUMAN (1-414): 5.68e-117: 374: 24.54
+	Hs
		789109 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		FRK_HUMAN (1-417): 1.07e-116: 373: 24.38
+	Hs
		433677 RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53		LYN_HUMAN (1-414): 5.68e-117: 374: 24.54
+	Hs
		433556 RAC2_HUMAN (1-192): 3.29e-77: 230: 55.16		LYN_HUMAN (1-414): 5.68e-117: 374: 24.54
+	Hs
		872522 RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73		EPHB4_HUMAN (88-409): 6.12e-98: 336: 30.68
+	Hs
		872518 RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53		EPHB4_HUMAN (88-409): 6.12e-98: 336: 30.68
+	Hs
		872525 RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21		EPHB4_HUMAN (88-409): 6.12e-98: 336: 30.68