HitPredict

Interactor 1: GLRB (P48167)
Glycine receptor subunit beta (Glycine receptor 58 kDa subunit)
Gene: GLRB

Interactor 2: GEPH (Q9NQX3)
Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)]
Gene: GPHN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	7546736, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0045211 - postsynaptic membrane GO:0097112 - gamma-aminobutyric acid receptor clustering and 1 others more... GO:0099572 - postsynaptic specialization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 497 Hs			1 736
+	Rn
		595705 GLRB_RAT (1-497): 2.25e-169: 488: 96.38		GEPH_RAT (1-736): 0: 1046: 95.70
+	Mm
		816696 GLRB_MOUSE (1-497): 6.47e-169: 487: 95.98		GEPH_MOUSE (1-736): 0: 1046: 95.58
+	Rn
		430003 GLRA1_RAT (38-496): 3.54e-143: 420: 42.55		GEPH_RAT (1-736): 0: 1046: 95.70
+	Rn
		590006 GBRA3_RAT (3-497): 8.37e-138: 408: 25.05		GEPH_RAT (1-736): 0: 1046: 95.70
+	Mm
		918821 GBRA1_MOUSE (43-497): 5.65e-134: 397: 28.11		GEPH_MOUSE (1-736): 0: 1046: 95.58
+	Rn
		588398 GBRA5_RAT (42-497): 1.62e-130: 388: 25.87		GEPH_RAT (1-736): 0: 1046: 95.70
+	Mm
		640296 GBRA2_MOUSE (46-497): 1.57e-127: 380: 28.73		GEPH_MOUSE (1-736): 0: 1046: 95.58