HitPredict

Interactor 1: IREB2 (P48200)
Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2)
Gene: IREB2

Interactor 2: FBXL5 (Q9UKA1)
F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein)
Gene: FBXL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.741

Property	Details
Experiments	31229404, 32126207, 35490179, 19762596, 19762597, 24778179
Identification Methods	pull down, affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006879 - intracellular iron ion homeostasis GO:0060586 - multicellular organismal-level iron ion homeostasis
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 691
+	Hs
		598710 ACOHC_HUMAN (8-963): 0: 1174: 54.64		FBXL5_HUMAN (1-691): 0: 1511: 100.00