HitPredict

Interactor 1: MTR3 (P48240)
Exosome complex component MTR3 (mRNA transport regulator 3)
Gene: MTR3

Interactor 2: RRP46 (P53256)
Exosome complex component RRP46 (Ribosomal RNA-processing protein 46)
Gene: RRP46

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 17942686, 11805826, 24336220, 12837249, 16429126, 27174052, 37968396
Identification Methods tandem affinity purification, affinity chromatography technology, biochemical
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNase_PH~RNase_PH, RNase_PH~RNase_PH_C
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
and 10 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 250
Sc

1 223
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024