Interactor 1: MTR3 (P48240)
Exosome complex component MTR3 (mRNA transport regulator 3)
Gene: MTR3

Interactor 2: RRP44 (Q08162)
Exosome complex exonuclease DIS3 (EC 3.1.13.-) (EC 3.1.26.-) (Chromosome disjunction protein 3) (Ribosomal RNA-processing protein 44)
Gene: DIS3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.90 0.922

The method score is based on:

Property Details
Experiments 12972615, 11805826, 16554755, 16429126, 37968396, 28877463, 17173052, 18314965, 19879841
Identification Methods coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains OB_Dis3~RNase_PH, RNB~RNase_PH
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
and 8 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024