HitPredict

Interactor 1: PI42A (P48426)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (PIP5KIII) (Phosphatidylinositol 5-Phosphate 4-Kinase) (PI5P4Kalpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(4)P-5-kinase B isoform) (PtdIns(4)P-5-kinase C isoform) (PtdIns(5)P-4-kinase isoform 2-alpha)
Gene: PIP4K2A

Interactor 2: STK11 (Q15831)
Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)
Gene: STK11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 433
+	Hs
		942414 PI42B_HUMAN (11-406): 3.27e-166: 474: 78.30		STK11_HUMAN (1-433): 8.74e-141: 411: 100.00
+	Hs
		1079112 PI42C_HUMAN (16-405): 1.05e-161: 462: 65.33		STK11_HUMAN (1-433): 8.74e-141: 411: 100.00
+	Zm
		34700 A0A1D6LDJ0_MAIZE (75-287): 1.34e-79: 269: 24.32		B5AU21_MAIZE (39-408): 2.16e-132: 390: 27.76