HitPredict

Interactor 1: PI42A (P48426)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (PIP5KIII) (Phosphatidylinositol 5-Phosphate 4-Kinase) (PI5P4Kalpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(4)P-5-kinase B isoform) (PtdIns(4)P-5-kinase C isoform) (PtdIns(5)P-4-kinase isoform 2-alpha)
Gene: PIP4K2A

Interactor 2: SAHH3 (Q96HN2)
Adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.13.2.1) (IP(3)Rs binding protein released with IP(3) 2) (IRBIT2) (Long-IRBIT) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2)
Gene: AHCYL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 611
+	Hs
		942436 PI42B_HUMAN (11-406): 3.27e-166: 474: 78.30		SAHH3_HUMAN (1-611): 0: 1042: 100.00
+	Hs
		1253112 PI42C_HUMAN (16-405): 1.05e-161: 462: 65.33		SAHH3_HUMAN (1-611): 0: 1042: 100.00
+	Hs
		1293637 PI51A_HUMAN (17-403): 3.34e-151: 441: 27.67		SAHH3_HUMAN (1-611): 0: 1042: 100.00
+	Hs
		216467 PI42A_HUMAN (1-406): 4.07e-180: 508: 100.00		SAHH2_HUMAN (110-611): 0: 843: 91.83
+	Hs
		216489 PI42B_HUMAN (11-406): 3.27e-166: 474: 78.30		SAHH2_HUMAN (110-611): 0: 843: 91.83
+	Hs
		216556 PI42C_HUMAN (16-405): 1.05e-161: 462: 65.33		SAHH2_HUMAN (110-611): 0: 843: 91.83