HitPredict

Interactor 1: PI42A (P48426)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (PIP5KIII) (Phosphatidylinositol 5-Phosphate 4-Kinase) (PI5P4Kalpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(4)P-5-kinase B isoform) (PtdIns(4)P-5-kinase C isoform) (PtdIns(5)P-4-kinase isoform 2-alpha)
Gene: PIP4K2A

Interactor 2: AFF4 (Q9UHB7)
AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein)
Gene: AFF4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 1163
+	Hs
		1253130 PI42C_HUMAN (16-405): 1.05e-161: 462: 65.33		AFF4_HUMAN (1-1163): 1.3e-124: 413: 100.00
+	Hs
		817642 PI42A_HUMAN (1-406): 4.07e-180: 508: 100.00		AFF1_HUMAN (4-1160): 4.79e-88: 312: 34.47
+	Hs
		817643 PI42A_HUMAN (1-406): 4.07e-180: 508: 100.00		AFF3_HUMAN (5-1161): 2.39e-69: 256: 31.28