HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001649 - osteoblast differentiation GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 1 others more... GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 1226
+	Hs
		877251 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		DSRAD_HUMAN (1-1226): 0: 1785: 100.00
+	Hs
		585419 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		E2AK2_HUMAN (505-857): 1.48e-55: 205: 18.45
+	Hs
		818304 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		DGCR8_HUMAN (474-762): 2.83e-47: 184: 17.94
+	Hs
		269652 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89
+	Hs
		818080 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		TRBP2_HUMAN (589-807): 3.88e-36: 143: 21.81
+	Hs
		818507 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		STAU2_HUMAN (470-829): 3.1e-28: 123: 17.54
+	Hs
		817990 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		322321 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Mm
		818779 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		ILF3_MOUSE (504-660): 1.56e-25: 116: 23.30
+	Hs
		331855 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		DGCR8_HUMAN (474-762): 2.83e-47: 184: 17.94
+	Hs
		269595 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89
+	Mm
		1142606 SOX17_MOUSE (7-290): 2.02e-35: 134: 27.59		ILF3_MOUSE (504-660): 1.56e-25: 116: 23.30
+	Hs
		996638 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		1019850 BBX_HUMAN (20-260): 9.07e-30: 121: 19.75		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		331797 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		322045 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Hs
		225700 SOX15_HUMAN (13-118): 1.78e-31: 119: 66.04		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Hs
		944755 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05
+	Hs
		944875 BBX_HUMAN (20-260): 9.07e-30: 121: 19.75		RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05
+	Hs
		331783 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05