HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 216
+	Hs
		817886 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00
+	Hs
		817852 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76
+	Hs
		817882 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94
+	Hs
		817854 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RAB10_HUMAN (11-177): 3.9e-29: 109: 33.14
+	Hs
		817806 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13