HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: PRDX1 (Q06830)
Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Gene: PRDX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21280222
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 199
+	Hs
		685636 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78
+	Hs
		670675 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50
+	Hs
		989368 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00
+	Hs
		685750 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78
+	Hs
		331794 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00
+	Hs
		1026778 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		1026752 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		670752 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50