HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: PWP1 (Q13610)
Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502)
Gene: PWP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	35140242, 34732716, 23667531
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 501
+	Hs
		245575 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		TBL1X_HUMAN (26-374): 1.02e-50: 183: 15.10
+	Hs
		818441 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		TBL1R_HUMAN (7-331): 4.59e-39: 150: 14.89
+	Mm
		1142008 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		TBL1R_MOUSE (7-331): 3.34e-39: 150: 14.89
+	Hs
		818834 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09
+	Hs
		1281404 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09
+	Hs
		1281409 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09
+	Hs
		881823 SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42		FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09
+	Hs
		996813 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09
+	Hs
		245569 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		TBL1X_HUMAN (26-374): 1.02e-50: 183: 15.10
+	Hs
		245636 SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19		TBL1X_HUMAN (26-374): 1.02e-50: 183: 15.10
+	Hs
		245585 SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42		TBL1X_HUMAN (26-374): 1.02e-50: 183: 15.10
+	Hs
		817868 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		WDR5_HUMAN (7-223): 2.82e-12: 69.6: 10.08
+	Hs
		245594 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		TBL1X_HUMAN (26-374): 1.02e-50: 183: 15.10
+	Hs
		1288324 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		SNR40_HUMAN (16-369): 1.71e-44: 162: 14.88
+	Hs
		1074805 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		TAF5_HUMAN (66-363): 3.47e-40: 156: 15.95
+	Hs
		989530 SOX4_HUMAN (9-289): 2.6e-33: 129: 26.69		TAF5_HUMAN (66-363): 3.47e-40: 156: 15.95
+	Hs
		1040837 SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19		PWP1_HUMAN (299-500): 6.9e-30: 124: 13.91
+	Hs
		989528 SOX4_HUMAN (9-289): 2.6e-33: 129: 26.69		PWP1_HUMAN (299-500): 6.9e-30: 124: 13.91
+	Hs
		903450 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		WDR5_HUMAN (7-223): 2.82e-12: 69.6: 10.08
+	Hs
		903169 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		WDR5_HUMAN (7-223): 2.82e-12: 69.6: 10.08