HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34591642
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 4684
+	Hs
		331816 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		PLEC_HUMAN (1-4684): 0: 1783: 100.00
+	Hs
		506811 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SPTB1_HUMAN (151-2274): 6.68e-124: 442: 17.12
+	Hs
		521599 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94
+	Hs
		164582 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SPTN2_HUMAN (1390-3166): 2.85e-25: 118: 12.24
+	Hs
		817925 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53
+	Hs
		818611 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		MACF1_HUMAN (3704-4616): 3.72e-10: 69.3: 14.92
+	Hs
		551635 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		DESP_HUMAN (351-874): 8.53e-10: 68.1: 8.21
+	Hs
		885297 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75
+	Hs
		963398 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53
+	Mm
		93555 SOX17_MOUSE (7-290): 2.02e-35: 134: 27.59		DESP_MOUSE (351-883): 3.06e-11: 72.7: 8.07
+	Hs
		551812 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		DESP_HUMAN (351-874): 8.53e-10: 68.1: 8.21